Aciclovir tablets treat genital herpes by slowing the herpes virus, helping sores heal faster and reducing pain, itching, and outbreaks. Take exactly as prescribed and complete the course. Start treatment as soon as symptoms begin for best results. Common side effects include headache, nausea, diarrhoea, and dizziness. Drink plenty of water while taking aciclovir. It does not cure herpes or completely prevent transmission to others.